"Little Girl Blue" is a popular song.

The music was written by Richard Rodgers, the lyrics by Lorenz Hart. The song was published in 1935. The song was introduced in the Broadway musical Jumbo.

Many popular and jazz artists have recorded the tune, including Nina Simone (whose 1958 debut album was named after the song), Sam Cooke, Frank Sinatra, Ella Fitzgerald, Judy Garland, Chet Baker, The Carpenters, Coleman Hawkins, Sarah Vaughan, Anita O'Day, Linda Ronstadt, Diana Ross, Johnny Hartman, Grant Green, The Postal Service, and even Janis Joplin (although the lyrics on this version were rearranged).