Kobra Khan is a fictional character in the popular Masters of the Universe toy line and the accompanying cartoon series He-Man and the Masters of the Universe.

He is a member of the Evil Warriors, and a cross between a man and a cobra, who has the power to spray a 'sleep mist' from his hood which immediately renders his opponent unconscious. Although generally recognized as a member of Skeletor's evil team, in many media he serves a dual allegiance to both Skeletor and King Hiss of the Snake Men.