13th SAG Awards January 28, 2007 Best Cast - Motion Picture: Little Miss Sunshine Best Cast - Drama Series: Grey's Anatomy Best Cast - Comedy Series: The Office The 13th Annual Screen Actors Guild Awards ceremony, honouring the best in film and television acting achievement for the year 2006, took place on 28 January, 2007 and, for the 11th consecutive ceremony, was held at the Los Angeles Shrine Exposition Center, in Los Angeles, California. The nominees were announced on 4 January, 2007. It was televised live on TNT and TBS and was the 10th consecutive year TNT televised the event and the second year for TBS

Babel, Dreamgirls and Little Miss Sunshine received the highest number of nominations among the film categories with each getting three, two for acting and one for ensemble performance, however only Dreamgirls won more than one award. In the television categories The Sopranos and Broken Trail had the most nominations with three but it was the mini-series Elizabeth I and the medical drama Grey's Anatomy which won the most awards with two each.

The Screen Actors Guild Life Achievement Award was presented to the actress Julie Andrews.